Road trip...to space! After learning some startling secrets about her family, Jessica Drew goes on a mission to find the one person who might know more: the High Evolutionary! But she's going to need her BFF by her side--and that means it's Captain Marvel team-up time! Before long, though, Spider-Woman will be abandoned by those closest to her--and only one person will come to her aid...Octavia Vermis! Octavia has a cure for Jessica, and the prescription is: crime! Is Jess willing to resort to theft to gather all the tools needed to fix what's wrong? In the shadow of Knull's invasion, Spider-Woman must put everything on the line...and then cross it! Even if Jess can find the cure for what ails her, will she still have a life worth saving?