The year is now 2027 and the world has reached a tipping point! The human population continues to dwindle due to the sterility problem and a devastating threat rises in the form of "the hybrids," an army of unstoppable lab-made creatures who are hellbent on destroying mankind. Although the team has become estranged over the past decade, Jackson, Jamie, Abraham, Dariela and Logan are forced to overcome their differences and reunite when they learn that Mitch is alive.